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Friday, May 07, 2010


One of my reader contacted through the Contact Us form and asked about which foods to be avoided while taking Amitriptyline. Amitriptyline is a drug that indicated for the treatment of major depression, as well as clinical or endogenous depression and also involutional melancholia or general depression. Amitriptyline is a Tricyclic Antidepressant drug which inhibit the serotonin-nor epinephrine reuptake and cause a localized increase in the active Nor Adrenaline around the synaptic gap of nerve endings. Amitriptyline cause blockade of presynaptic alpha 2 adrenoreceptors.

AMITRIPTYLINE In different countries, Amitriptyline is available as OTC drug and in some other, available as POM( Prescription Only Medicine)

Avoid drinking alcohol while taking Amitriptyline. It can cause dangerous side effects when taken together with amitriptyline like synergizing the mood elevation.

Grapefruit and grapefruit juice may interact with Amitriptyline.

Any food that contain enzymes Mono Amino Oxidase or similar will work against the action of Amitriptyline. Also foods that are rich source of DOPA ( Dihydroxy phenylalanine) will synergize the action of Amitriptyline.

Broad Beans are rich source of DOPA,  which may increase the blood level of Nor Adrenaline in blood. If you take Amitriptyline, and broad beans together, then the amount of active Nor adrenaline increases which may cause serious side effects like increase in blood pressure.

Never take Yoghurt, buttermilk, meat extracts, soya beans, chocolate and banana  peels in huge quantities when you are in treatment with Amitriptyline.

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